(2-Amino-5-cyclopropylmethoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (5-Cyclopropylmethoxy-2-{3-[3-(6-cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:23])[cH:10][c:11]([C:19]([F:20])([F:21])[F:22])[c:12]([O:14][CH2:15][CH:16]2[CH2:17][CH2:18]2)[cH:13]1)=[O:24].[C:25]([CH3:27])([CH3:28])([O:29][C:30](=[O:26])[CH2:31][C:32](=[O:33])[c:34]1[cH:35][c:36](-[c:40]2[cH:41][n:42][c:43]([CH:46]3[CH2:47][CH2:48]3)[cH:44][cH:45]2)[cH:37][cH:38][cH:39]1)[CH3:49]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:23][C:30](=[O:29])[CH2:31][C:32](=[O:33])[c:34]2[cH:35][c:36](-[c:40]3[cH:41][n:42][c:43]([CH:46]4[CH2:47][CH2:48]4)[cH:44][cH:45]3)[cH:37][cH:38][cH:39]2)[cH:10][c:11]([C:19]([F:20])([F:21])[F:22])[c:12]([O:14][CH2:15][CH:16]2[CH2:17][CH2:18]2)[cH:13]1)=[O:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-15122ef326084ba1841e9c5fb92de3e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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