5-bromo-N-(1,3-dihydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[7-Cyclopropyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amide
Reaction equation
[CH:1]1([c:4]2[cH:5][c:6](-[c:15]3[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]3)[n:7][c:8]3[n:9]2[n:10][cH:11][c:12]3[C:13]#[CH:14])[CH2:2][CH2:3]1.[OH:25][CH2:26][C:27]([CH3:28])([CH2:29][OH:30])[NH:31][S:32](=[O:33])(=[O:34])[c:35]1[cH:36][n:37][cH:38][c:39]([Br:41])[cH:40]1>>[CH:1]1([c:4]2[cH:5][c:6](-[c:15]3[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]3)[n:7][c:8]3[n:9]2[n:10][cH:11][c:12]3[C:13]#[C:14][c:39]2[cH:38][n:37][cH:36][c:35]([S:32]([NH:31][C:27]([CH2:26][OH:25])([CH3:28])[CH2:29][OH:30])(=[O:33])=[O:34])[cH:40]2)[CH2:2][CH2:3]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-507e1c32023a4e12b899e227b91ca83f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…