Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1547422Generated: November 1, 2026

Hydrochloric Acid → N1-(3-Fluoro-4-(2-(2-morpholinoethylamino)pyridin-4-yloxy)phenyl)-N3-(4-fluorophenyl)malonamide

https://huagongshe.com/reaction/1547422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantTetrafluoroborateHCID 26255—
ReactantDiisopropylethylamineHCID 81531—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant1-(4-(6-Aminopyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)thioureaHCID 11538912—
ReactantN1-(4-(2-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-N3-(4-fluorophenyl)malonamideHCID 59852883—
Reactant4-(4-amino-2-fluorophenoxy)-N-(2-morpholin-4-ylethyl)pyridin-2-amineHCID 59852915—
ProductN1-(3-Fluoro-4-(2-(2-morpholinoethylamino)pyridin-4-yloxy)phenyl)-N3-(4-fluorophenyl)malonamideHCID 59852917—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-85cba2b449094c4d817de36f2186604a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)