Potassium Cation → 2-[4-(1-Hydroxy-1-methylethyl)phenyl]-5-{[6-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl]amino}-1,3-thiazole-4-carboxamide
Reaction equation
[Br:20][c:21]1[cH:22][cH:23][cH:24][c:25]([CH:27]([C:28]([F:29])([F:30])[F:31])[OH:32])[n:26]1.[C:33](=[O:34])([O-:35])[O-:36].[C:39]([OH:40])([CH2:41][CH3:42])([CH3:43])[CH3:44].[K+:37].[K+:38].[NH2:1][c:2]1[c:3]([C:17](=[O:18])[NH2:19])[n:4][c:5](-[c:7]2[cH:8][cH:9][c:10]([C:13]([CH3:14])([CH3:15])[OH:16])[cH:11][cH:12]2)[s:6]1.[O:47]=[C:48]([CH:49]=[CH:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1.[O:65]=[C:66]([CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1)[CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1.[O:83]=[C:84]([CH:85]=[CH:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1)[CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1.[Pd:45].[Pd:46]>>[NH:1]([c:2]1[c:3]([C:17](=[O:18])[NH2:19])[n:4][c:5](-[c:7]2[cH:8][cH:9][c:10]([C:13]([CH3:14])([CH3:15])[OH:16])[cH:11][cH:12]2)[s:6]1)[c:21]1[cH:22][cH:23][cH:24][c:25]([CH:27]([C:28]([F:29])([F:30])[F:31])[OH:32])[n:26]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-125d1eefc61d4a949670932dd140d2f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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