1'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one → 1'-{[6-Chloro-1-(pyrimidin-5-ylmethyl)-1H-indol-3-yl]carbonyl}-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][nH:8][c:9]2[cH:10]1.[n:29]1[cH:30][n:31][cH:32][c:33]([CH2:35][O:36][S:37]([CH3:38])(=[O:39])=[O:40])[cH:34]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][n:8]([CH2:35][c:33]3[cH:32][n:31][cH:30][n:29][cH:34]3)[c:9]2[cH:10]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3f1da3dc1f59461fadf4af9449db264e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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