Methanol → (+)-2-(4-Aminomethyl-3-fluoro-phenoxy)-propionic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([CH3:8])[O:9][c:10]1[cH:11][c:12]([F:18])[c:13]([C:16]#[N:17])[cH:14][cH:15]1)=[O:19].[CH3:22][OH:23].[H:20][H:21].[OH-:24].[OH-:26].[Pd+2:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([CH3:8])[O:9][c:10]1[cH:11][c:12]([F:18])[c:13]([CH2:16][NH2:17])[cH:14][cH:15]1)=[O:19]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-81306a9df0c541c3a3ae6662b2fa8dbb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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