Methanol → 8-hydroxy-5-{1-hydroxy-2-[1-(4-trifluoromethyl-benzyl)-cyclopropylamino]-ethyl}-1H-quinolin-2-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([CH:20]([CH2:21][NH:22][C:23]2([CH2:26][c:27]3[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:32]3)[CH2:24][CH2:25]2)[OH:37])[c:13]2[cH:14][cH:15][c:16](=[O:19])[nH:17][c:18]12.[CH3:38][OH:39]>>[OH:8][c:9]1[cH:10][cH:11][c:12]([CH:20]([CH2:21][NH:22][C:23]2([CH2:26][c:27]3[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:32]3)[CH2:24][CH2:25]2)[OH:37])[c:13]2[cH:14][cH:15][c:16](=[O:19])[nH:17][c:18]12Participants
3
Sources & evidence
- ORD record
- ord-4685e5aab3bb4986997df856e05c6429
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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