1-(Bromomethyl)-4-(trifluoromethyl)benzene → Ethyl 4-methyl-2-(2-oxo-3-(quinolin-8-ylmethyl)imidazolidin-1-yl)thiazole-5-carboxylate
Reaction equation
[Br:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][c:19]2[cH:20][cH:21][cH:22][n:23][c:24]12.[CH3:25][c:26]1[n:27][c:28]([N:36]2[C:37](=[O:41])[NH:38][CH2:39][CH2:40]2)[s:29][c:30]1[C:31](=[O:32])[O:33][CH2:34][CH3:35].[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][Br:10])[cH:11][cH:12]1>>[CH2:14]([c:15]1[cH:16][cH:17][cH:18][c:19]2[cH:20][cH:21][cH:22][n:23][c:24]12)[N:38]1[C:37](=[O:41])[N:36]([c:28]2[n:27][c:26]([CH3:25])[c:30]([C:31](=[O:32])[O:33][CH2:34][CH3:35])[s:29]2)[CH2:40][CH2:39]1Participants
4
Sources & evidence
- ORD record
- ord-0a8886e9f05044dab404b807e39e55fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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