2-(7-Amino-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-acetamide → 2-{7-[7-(3-Cyclopropylsulfamoyl-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino]-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl}-acetamide

HRID 1548919Notes

Reaction equation

HRID 1548919 reaction equation
[CH:1]1([NH:4][S:5](=[O:6])(=[O:7])[c:8]2[cH:9][c:10](-[c:14]3[cH:15][cH:16][c:17]4[cH:18][n:19][c:20]([OH:23])[n:21][n:22]34)[cH:11][cH:12][cH:13]2)[CH2:2][CH2:3]1.[NH2:24][c:25]1[cH:26][c:27]2[c:28]([cH:38][c:39]1[O:40][CH3:41])[CH2:29][CH2:30][N:31]([CH2:34][C:35](=[O:36])[NH2:37])[CH2:32][CH2:33]2>>[CH:1]1([NH:4][S:5](=[O:6])(=[O:7])[c:8]2[cH:9][c:10](-[c:14]3[cH:15][cH:16][c:17]4[cH:18][n:19][c:20]([NH:24][c:25]5[cH:26][c:27]6[c:28]([cH:38][c:39]5[O:40][CH3:41])[CH2:29][CH2:30][N:31]([CH2:34][C:35](=[O:36])[NH2:37])[CH2:32][CH2:33]6)[n:21][n:22]34)[cH:11][cH:12][cH:13]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 667114642-(7-Amino-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-acetamideHCID 178527450HCID 178527450, compound

Product 1

HCID 667122102-{7-[7-(3-Cyclopropylsulfamoyl-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino]-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl}-acetamide

Sources & evidence

ORD record
ord-5020191366144f2cbf9c68d42baa7894
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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