Acetonitrile → (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine

HRID 1548953Notes

Reaction equation

HRID 1548953 reaction equation
[CH3:29][C:30]#[N:31].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][n:9][c:10]([Cl:12])[cH:11]2.[F:13][c:14]1[cH:15][c:16]([CH2:17][O:18][c:19]2[cH:20][cH:21][c:22]([NH2:23])[cH:24][cH:25]2)[cH:26][cH:27][cH:28]1>>[c:2]1([NH:23][c:22]2[cH:21][cH:20][c:19]([O:18][CH2:17][c:16]3[cH:15][c:14]([F:13])[cH:28][cH:27][cH:26]3)[cH:25][cH:24]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][n:9][c:10]([Cl:12])[cH:11]2

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 108218764,6-Dichloropyrido[3,4-d]pyrimidineHCID 167753144-(3-Fluoro-benzyloxy)-phenylamine

Product 1

HCID 21952062(6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine

Sources & evidence

ORD record
ord-bad363aa721f4445bb821c0ee362db9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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