3-[(4-Chlorophenyl)(cyclopropyl)methyl]-7-[(methylsulfinyl)methyl]-1H-indole → 3-[(4-Chloro-2,6-difluorophenyl)(cyclopropyl)methyl]-7-[(methylsulfinyl)methyl]-1H-indole
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([F:25])[c:5]([CH:9]([c:10]2[cH:11][nH:12][c:13]3[c:14]([CH2:19][S:20][CH3:21])[cH:15][cH:16][cH:17][c:18]23)[CH:22]2[CH2:23][CH2:24]2)[c:6]([F:8])[cH:7]1.[Cl:26][c:27]1[cH:28][cH:29][c:30]([CH:31]([CH:32]2[CH2:33][CH2:34]2)[c:35]2[c:36]3[c:37]([c:38]([CH2:39][S:40]([CH3:41])=[O:45])[cH:42][cH:43][cH:44]3)[nH:46][cH:47]2)[cH:48][cH:49]1>>[Cl:1][c:2]1[cH:3][c:4]([F:25])[c:5]([CH:9]([c:10]2[cH:11][nH:12][c:13]3[c:14]([CH2:19][S:20]([CH3:21])=[O:45])[cH:15][cH:16][cH:17][c:18]23)[CH:22]2[CH2:23][CH2:24]2)[c:6]([F:8])[cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-1c7fcf1aa8fb4abb976b2452edce6b5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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