1,1-Dichloroethane → 1-Boc-4-ethoxycarbonylmethoxypiperidine

HRID 1549014Notes

Reaction equation

HRID 1549014 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[Cl:23][CH:24]([Cl:25])[CH3:26].[N+:15](=[N-:16])=[CH:17][C:18](=[O:19])[O:20][CH2:21][CH3:22]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][CH2:17][C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 63651,1-DichloroethaneHCID 12192Ethyl diazoacetateHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Product 1

HCID 105173911-Boc-4-ethoxycarbonylmethoxypiperidine

Sources & evidence

ORD record
ord-33eb3fe0907a4b0b857b33f5a7a420c4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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