3-Fluorobenzyl chloride → N-[2-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-5-yl]oxypropyl]-N-methylacetamide
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]3[cH:15][cH:16][cH:17][c:18]([O:20][CH:21]([CH2:22][N:23]([C:24]([CH3:25])=[O:26])[CH3:27])[CH3:28])[c:19]23)[cH:5][cH:6][c:7]1[OH:8].[F:29][c:30]1[cH:31][c:32]([CH2:33][Cl:34])[cH:35][cH:36][cH:37]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]3[cH:15][cH:16][cH:17][c:18]([O:20][CH:21]([CH2:22][N:23]([C:24]([CH3:25])=[O:26])[CH3:27])[CH3:28])[c:19]23)[cH:5][cH:6][c:7]1[O:8][CH2:33][c:32]1[cH:31][c:30]([F:29])[cH:37][cH:36][cH:35]1Participants
3
Sources & evidence
- ORD record
- ord-fe93fa3c9a304dc984ac46657bec55ad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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