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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1549366Generated: October 31, 2026

Hydrochloric Acid → N-[3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carboxamide

https://huagongshe.com/reaction/1549366

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant3-(Piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-oneHCID 11379587—
Reactant2-Amino-3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-1-(4-piperidin-1-ylpiperidin-1-yl)propan-1-oneHCID 69159507—
ProductN-[3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carboxamideHCID 10372583—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-1005bd870e7c472cb9b84cfff4cc7c77
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)