2,3-Dichloro-5-(trifluoromethyl)pyridine → 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-3-chloro-5-trifluoromethylpyridine

HRID 1549651Notes

Reaction equation

HRID 1549651 reaction equation
[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([O:19][CH3:20])[c:15]([Cl:18])[cH:16][cH:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Cl:21][c:22]1[c:23]([Cl:24])[cH:25][c:26]([C:27]([F:28])([F:29])[F:30])[cH:31][n:32]1.[Cl:33][c:34]1[c:35]([O:36][CH3:37])[cH:38][c:39]([B:40]([OH:41])[OH:42])[c:43]([F:44])[cH:45]1>>[Cl:1][c:2]1[c:3](-[c:12]2[cH:13][c:14]([O:19][CH3:20])[c:15]([Cl:18])[cH:16][c:17]2[F:30])[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

4

Reactant 3

HCID 1122342,3-Dichloro-5-(trifluoromethyl)pyridineHCID 10932600(4-Chloro-2-fluoro-5-methoxyphenyl)boronic acidHCID 157668763-Chloro-2-(4-chloro-3-methoxyphenyl)-5-trifluoromethylpyridine

Product 1

HCID 110022952-(4-Chloro-2-fluoro-5-methoxyphenyl)-3-chloro-5-trifluoromethylpyridine

Sources & evidence

ORD record
ord-5e6c48bd41db4a05903e976722206e58
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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