tert-Butyl acetate → (RS)-3-Oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-3-yl]-phenyl}-propionic acid tert.-butyl ester
Reaction equation
[C:24]([CH3:25])(=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6](-[c:10]2[n:11][o:12][c:13]([CH2:15][O:16][CH:17]3[O:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[cH:14]2)[cH:7][cH:8][cH:9]1)=[O:23].[Li:32]>>[C:3]([c:4]1[cH:5][c:6](-[c:10]2[n:11][o:12][c:13]([CH2:15][O:16][CH:17]3[O:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[cH:14]2)[cH:7][cH:8][cH:9]1)(=[O:23])[CH2:25][C:24](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31]Participants
4
Sources & evidence
- ORD record
- ord-d4e10a84a4754ac98717ef69dbabe6a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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