2-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine → 2-Methyl-2-(4-{[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylcarbamoyl]-methyl}-phenoxy)-propionic acid tert-butyl ester
Reaction equation
[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24]([C:25]([CH3:26])([CH3:27])[O:28][c:29]1[cH:30][cH:31][c:32]([CH2:35][C:36](=[O:37])[OH:38])[cH:33][cH:34]1)=[O:39].[CH3:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:5][cH:6][c:7]1[NH2:8]>>[CH3:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[cH:5][cH:6][c:7]1[NH:8][C:36]([CH2:35][c:32]1[cH:31][cH:30][c:29]([O:28][C:25]([C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:39])([CH3:26])[CH3:27])[cH:34][cH:33]1)=[O:37]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a72057c07fe84f0da79edab9631da67b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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