Pyridine → 1-[4-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-2-yl]-3-(2-fluoro-phenyl)-urea
Reaction equation
[F:1][c:2]1[c:3]([N:8]=[C:9]=[O:10])[cH:4][cH:5][cH:6][cH:7]1.[NH2:11][c:12]1[c:13]2[c:14]([n:15][cH:16][n:17]1)[n:18]([CH:30]([CH3:31])[CH3:32])[cH:19][c:20]2[C:21](=[O:22])[c:23]1[cH:24][c:25]([NH2:29])[n:26][cH:27][cH:28]1.[cH:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1>>[F:1][c:2]1[c:3]([NH:8][C:9](=[O:10])[NH:29][c:25]2[cH:24][c:23]([C:21]([c:20]3[c:13]4[c:12]([NH2:11])[n:17][cH:16][n:15][c:14]4[n:18]([CH:30]([CH3:31])[CH3:32])[cH:19]3)=[O:22])[cH:28][cH:27][n:26]2)[cH:4][cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-434eb3f3072e4fe69af4124055fdfbf6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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