4-(4-(Trifluoromethoxy)phenyl)piperidine → N-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-2-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]acetamide

HRID 155038Notes

Reaction equation

HRID 155038 reaction equation
[Cl:1][CH2:2][C:3](=[O:4])[NH:5][CH:6]1[CH2:7][n:8]2[c:9]([n:12][c:13]([N+:15](=[O:16])[O-:17])[cH:14]2)[O:10][CH2:11]1.[F:18][C:19]([O:20][c:21]1[cH:22][cH:23][c:24]([CH:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[cH:25][cH:26]1)([F:33])[F:34]>>[CH2:2]([C:3](=[O:4])[NH:5][CH:6]1[CH2:7][n:8]2[c:9]([n:12][c:13]([N+:15](=[O:16])[O-:17])[cH:14]2)[O:10][CH2:11]1)[N:30]1[CH2:29][CH2:28][CH:27]([c:24]2[cH:23][cH:22][c:21]([O:20][C:19]([F:18])([F:33])[F:34])[cH:26][cH:25]2)[CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 212682884-(4-(Trifluoromethoxy)phenyl)piperidineHCID 774252592-chloro-N-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)acetamide

Product 1

HCID 89453277N-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-2-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]acetamide

Sources & evidence

ORD record
ord-0c8e6f5ac6f24fb280decde2a4848849
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…