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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1550461Generated: November 2, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → 1-(2-Fluoro-4-(3-(4-methylpiperazin-1-yl)pyrido[3,2-b]pyrazin-8-yloxy)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

https://huagongshe.com/reaction/1550461

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
Reactant2-Fluoro-4-(3-(4-methylpiperazin-1-yl)pyrido[3,2-b]pyrazin-8-yloxy)anilineHCID 46901761—
Product1-(2-Fluoro-4-(3-(4-methylpiperazin-1-yl)pyrido[3,2-b]pyrazin-8-yloxy)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)ureaHCID 44133016—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-bb2f6d96bf1f4e0ca333fb8ad32cc2a2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)