5-chloro-3-[2-(phenoxymethyl)morpholin-4-yl]sulfonyl-1H-indole-2-carboxamide → 5-bromo-3-[2-(phenoxymethyl)morpholin-4-yl]sulfonyl-1H-indole-2-carboxamide

HRID 1550745Notes

Reaction equation

HRID 1550745 reaction equation
[CH2:31]([O:32][C:33]([c:34]1[n:35]([S:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)(=[O:43])=[O:44])[c:45]2[c:46]([c:47]1[S:48]([N:49]1[CH2:50][CH2:51][O:52][CH:53]([CH2:54][O:55][c:56]3[cH:57][cH:58][cH:59][cH:60][cH:61]3)[CH2:62]1)(=[O:63])=[O:64])[cH:65][c:66]([Cl:67])[cH:68][cH:69]2)=[O:70])[CH3:71].[CH2:72]([O:73][C:74]([c:75]1[n:76]([S:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)(=[O:84])=[O:85])[c:86]2[c:87]([c:88]1[S:89]([N:90]1[CH2:91][CH2:92][O:93][CH:94]([CH2:95][O:96][c:97]3[cH:98][cH:99][cH:100][cH:101][cH:102]3)[CH2:104]1)(=[O:105])=[O:106])[cH:107][c:108]([Br:103])[cH:109][cH:110]2)=[O:111])[CH3:112].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([S:14](=[O:15])(=[O:16])[N:17]3[CH2:18][CH:19]([CH2:23][O:24][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[O:20][CH2:21][CH2:22]3)[c:6]([C:11](=[O:12])[NH2:13])[nH:7][c:8]2[cH:9][cH:10]1>>[c:2]1([Br:103])[cH:3][c:4]2[c:5]([S:14](=[O:15])(=[O:16])[N:17]3[CH2:18][CH:19]([CH2:23][O:24][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[O:20][CH2:21][CH2:22]3)[c:6]([C:11](=[O:12])[NH2:13])[nH:7][c:8]2[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 104789085-chloro-3-[2-(phenoxymethyl)morpholin-4-yl]sulfonyl-1H-indole-2-carboxamideHCID 68442943ethyl 5-bromo-3-{[2-(phenoxymethyl)morpholin-4-yl]sulfonyl}-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 68878207Ethyl (+/-)-5-chloro-3-{[2-(phenoxymethyl)morpholin-4-yl]sulfonyl}-1-(phenylsulfonyl)-1h-indole-2-carboxylate

Product 1

HCID 103684625-bromo-3-[2-(phenoxymethyl)morpholin-4-yl]sulfonyl-1H-indole-2-carboxamide

Sources & evidence

ORD record
ord-1fd4b9d0b7b648cf8f1b8ea2a81f0aeb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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