Methanol → (RS)-1-[5-(4-Fluoro-phenyl)-2-methyl-thiazol-4-yl]-1-{2-[4-(1-hydroxy-ethyl)-1H-benzoimidazol-2-ylmethyl]-piperidin-1-yl}-methanone
Reaction equation
[BH4-:1].[C:3]([CH3:4])(=[O:5])[c:6]1[cH:7][cH:8][cH:9][c:10]2[nH:11][c:12]([CH2:15][CH:16]3[N:17]([C:22](=[O:23])[c:24]4[n:25][c:26]([CH3:36])[s:27][c:28]4-[c:29]4[cH:30][cH:31][c:32]([F:35])[cH:33][cH:34]4)[CH2:18][CH2:19][CH2:20][CH2:21]3)[n:13][c:14]12.[CH3:38][OH:39].[Na+:2].[OH2:37]>>[CH:3]([CH3:4])([OH:5])[c:6]1[cH:7][cH:8][cH:9][c:10]2[nH:11][c:12]([CH2:15][CH:16]3[N:17]([C:22](=[O:23])[c:24]4[n:25][c:26]([CH3:36])[s:27][c:28]4-[c:29]4[cH:30][cH:31][c:32]([F:35])[cH:33][cH:34]4)[CH2:18][CH2:19][CH2:20][CH2:21]3)[n:13][c:14]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d7dffcd9fa8f4cac94358150c460a3c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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