Chloroform → 6-Bromo-5-piperidin-1-yl-pyrazine-2-carboxylic acid methyl ester
Reaction equation
[Br:17][N:18]1[C:19](=[O:20])[CH2:21][CH2:22][C:23]1=[O:24].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[n:9][cH:10]1.[Cl:25][CH:26]([Cl:27])[Cl:28]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:17])[c:8]([N:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[n:9][cH:10]1Participants
4
Sources & evidence
- ORD record
- ord-5f1a3bc87bce478194e7bb875367faff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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