Dimethyl Sulfoxide → N-(4-Bromo-1-methylpyrazol-3-yl)-7-chloro-5-methoxy-1,2,4-triazolo[1,5-c]-pyrimidine-2-sulfonamide

HRID 1551525Notes

Reaction equation

HRID 1551525 reaction equation
[CH3:35][C:36]#[N:37].[CH3:7][S:8](=[O:9])[CH3:10].[Cl:11][c:12]1[cH:13][c:14]2[n:15]([c:16]([O:18][CH3:19])[n:17]1)[n:20][c:21]([S:23](=[O:24])(=[O:25])[Cl:26])[n:22]2.[NH2:27][c:28]1[n:29][n:30]([CH3:34])[cH:31][c:32]1[Br:33].[cH:1]1[cH:2][cH:3][n:4][cH:5][cH:6]1>>[Cl:11][c:12]1[cH:13][c:14]2[n:15]([c:16]([O:18][CH3:19])[n:17]1)[n:20][c:21]([S:23](=[O:24])(=[O:25])[NH:27][c:28]1[n:29][n:30]([CH3:34])[cH:31][c:32]1[Br:33])[n:22]2

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 1049PyridineHCID 6342AcetonitrileHCID 27352834-bromo-1-methyl-1H-pyrazol-3-amineHCID 150036517-Chloro-5-methoxy-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonyl chloride

Product 1

HCID 19768914N-(4-Bromo-1-methylpyrazol-3-yl)-7-chloro-5-methoxy-1,2,4-triazolo[1,5-c]-pyrimidine-2-sulfonamide

Sources & evidence

ORD record
ord-28089a0e85454751b481caf3eedb2ed6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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