2,5-Difluorophenylacetyl chloride → 2-(2,5-difluorophenyl)-1-(7-iodo-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-1-yl)ethanone
Reaction equation
[F:12][c:13]1[c:14]([CH2:20][C:21](=[O:22])[Cl:23])[cH:15][c:16]([F:19])[cH:17][cH:18]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:10][cH:11]1)[NH:6][CH2:7][CH2:8][NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:10][cH:11]1)[NH:6][CH2:7][CH2:8][N:9]2[C:21]([CH2:20][c:14]1[c:13]([F:12])[cH:18][cH:17][c:16]([F:19])[cH:15]1)=[O:22]Participants
3
Sources & evidence
- ORD record
- ord-8cd36f59e451440c99409d8e74be898c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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