3-Chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridine → 3-{3-Methyl-4-[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylmethoxy]-phenyl}-propionic acid ethyl ester

HRID 155198Notes

Reaction equation

HRID 155198 reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][c:7]1[cH:8][c:9]([CH3:14])[c:10]([OH:13])[cH:11][cH:12]1)=[O:15].[Cl:16][CH2:17][c:18]1[c:19]([CH3:34])[n:20][c:21](-[c:24]2[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]2)[cH:22][cH:23]1>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][c:7]1[cH:8][c:9]([CH3:14])[c:10]([O:13][CH2:17][c:18]2[c:19]([CH3:34])[n:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]3)[cH:22][cH:23]2)[cH:11][cH:12]1)=[O:15]

Participants

3

Reactant 2

HCID 219357513-Chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridineHCID 586298553-(4-Hydroxy-3-methyl-phenyl)-propionic acid ethyl ester

Product 1

HCID 670721983-{3-Methyl-4-[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylmethoxy]-phenyl}-propionic acid ethyl ester

Sources & evidence

ORD record
ord-751505abc4d942dfadddec309f0788f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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