1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-one → [8-(3,4-Difluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine

HRID 1552058Notes

Reaction equation

HRID 1552058 reaction equation
[CH3:19][c:20]1[n:21][s:22][c:23]([N:25]2[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]2)[n:24]1.[F:1][c:2]1[cH:3][c:4](-[c:9]2[c:10]3[n:11]([cH:12][cH:13][cH:14]2)[n:15][c:16]([NH2:18])[n:17]3)[cH:5][cH:6][c:7]1[F:8]>>[F:1][c:2]1[cH:3][c:4](-[c:9]2[c:10]3[n:11]([cH:12][cH:13][cH:14]2)[n:15][c:16]([NH:18][CH:28]2[CH2:27][CH2:26][N:25]([c:23]4[s:22][n:21][c:20]([CH3:19])[n:24]4)[CH2:30][CH2:29]2)[n:17]3)[cH:5][cH:6][c:7]1[F:8]

Participants

3

Reactant 2

HCID 592585101-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-oneHCID 673372048-(3,4-Difluorophenyl)-[1,2,4]triazolo[1,5-A]pyridin-2-amine

Product 1

HCID 53353628[8-(3,4-Difluoro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine

Sources & evidence

ORD record
ord-a0b14dc470a6494ea35e51401ec20ad5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…