4-(3-Chloro 4-fluoro-phenylamino)-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one → 4-(3-chloro-4-fluoro-phenylamino)-5-[5-(2-dimethylamino-ethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-ylmethylene]-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:17])[c:7]2[c:8]([nH:11][c:12]([CH:15]=[O:16])[c:13]2[CH3:14])[CH2:9][CH2:10]1)[CH3:18].[Cl:19][c:20]1[cH:21][c:22]([NH:27][c:28]2[c:29]3[c:30]([n:31][cH:32][n:33]2)[NH:34][C:35](=[O:37])[CH2:36]3)[cH:23][cH:24][c:25]1[F:26]>>[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:17])[c:7]2[c:8]([nH:11][c:12]([CH:15]=[C:36]3[c:29]4[c:28]([NH:27][c:22]5[cH:21][c:20]([Cl:19])[c:25]([F:26])[cH:24][cH:23]5)[n:33][cH:32][n:31][c:30]4[NH:34][C:35]3=[O:37])[c:13]2[CH3:14])[CH2:9][CH2:10]1)[CH3:18]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c535d8a6ef8f48ecae874a19e269d760
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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