Toluene → 2-[2-(3-Bromo-phenyl)-2-hydroxy-propoxy]-3,3,3-trifluoro-2-methyl-propionic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([C:4]([C:5]([F:6])([F:7])[F:8])([CH3:9])[O:10][CH2:11][C:12](=[O:13])[c:14]1[cH:15][c:16]([Br:20])[cH:17][cH:18][cH:19]1)=[O:21].[CH3:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].[CH3:29][Li:30].[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1>>[CH3:1][O:2][C:3]([C:4]([C:5]([F:6])([F:7])[F:8])([CH3:9])[O:10][CH2:11][C:12]([OH:13])([c:14]1[cH:15][c:16]([Br:20])[cH:17][cH:18][cH:19]1)[CH3:22])=[O:21]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-05fba5f7fa294c68867ca967178d443a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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