Dichloromethane → 4-{[(3-Chloro-pyrazin-2-yl)-(2-phenyl-quinolin-7-yl)-methyl]carbamoyl}-piperidine-1-carboxylic acid benzyl ester

HRID 1553400Notes

Reaction equation

HRID 1553400 reaction equation
[CH2:26]([c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1)[O:33][C:34](=[O:35])[N:36]1[CH2:37][CH2:38][CH:39]([C:42](=[O:43])[Cl:44])[CH2:40][CH2:41]1.[Cl:1][c:2]1[c:3]([CH:8]([c:9]2[cH:10][cH:11][c:12]3[cH:13][cH:14][c:15](-[c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[n:16][c:17]3[cH:18]2)[NH2:25])[n:4][cH:5][cH:6][n:7]1.[Cl:45][CH2:46][Cl:47]>>[Cl:1][c:2]1[c:3]([CH:8]([c:9]2[cH:10][cH:11][c:12]3[cH:13][cH:14][c:15](-[c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[n:16][c:17]3[cH:18]2)[NH:25][C:42]([CH:39]2[CH2:38][CH2:37][N:36]([C:34]([O:33][CH2:26][c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)=[O:35])[CH2:41][CH2:40]2)=[O:43])[n:4][cH:5][cH:6][n:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 2776270Benzyl 4-(chlorocarbonyl)piperidine-1-carboxylateHCID 51051365(3-Chloropyrazin-2-yl)(2-phenylquinolin-7-yl)methanamine

Product 1

HCID 576810294-{[(3-Chloro-pyrazin-2-yl)-(2-phenyl-quinolin-7-yl)-methyl]carbamoyl}-piperidine-1-carboxylic acid benzyl ester

Sources & evidence

ORD record
ord-513580b7df764f76b4a8921670abb0b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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