6-Methyl-1,2,3,4-tetrahydroquinoline → (6-Methyl-3,4-dihydro-2H-quinolin-1-yl)-[2-(3-trifluoromethyl-phenoxy)-pyridin-3-yl]-methanone
Reaction equation
[CH3:21][c:22]1[cH:23][c:24]2[c:29]([cH:30][cH:31]1)[NH:28][CH2:27][CH2:26][CH2:25]2.[F:1][C:2]([c:3]1[cH:4][c:5]([O:6][c:7]2[c:8]([C:9](=[O:10])[OH:11])[cH:12][cH:13][cH:14][n:15]2)[cH:16][cH:17][cH:18]1)([F:19])[F:20]>>[F:1][C:2]([c:3]1[cH:4][c:5]([O:6][c:7]2[c:8]([C:9](=[O:11])[N:28]3[CH2:27][CH2:26][CH2:25][c:24]4[cH:23][c:22]([CH3:21])[cH:31][cH:30][c:29]43)[cH:12][cH:13][cH:14][n:15]2)[cH:16][cH:17][cH:18]1)([F:19])[F:20]Participants
3
Sources & evidence
- ORD record
- ord-aaa3bdcf51e14897bfc6b2c529f47633
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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