Acetonitrile → methyl 5-[5-[[2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl]-methylamino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-3,4-dihydro-2H-pyrrole-2-carboxylate
Reaction equation
[Ag+:56].[CH3:45][C:46]#[N:47].[F:48][C:49]([F:50])([F:51])[S:52]([O-:53])(=[O:54])=[O:55].[NH2:1][CH:2]([C:3](=[O:4])[O:5][CH3:6])[CH2:7][C:8]#[C:9][c:10]1[n:11][cH:12][c:13]([N:24]([CH3:25])[C:26]([C:27]([CH3:28])([CH3:29])[c:30]2[cH:31][c:32]([C:40]([F:41])([F:42])[F:43])[cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]2)=[O:44])[c:14](-[c:16]2[c:17]([CH3:23])[cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:15]1>>[N:1]1=[C:9]([c:10]2[n:11][cH:12][c:13]([N:24]([CH3:25])[C:26]([C:27]([CH3:28])([CH3:29])[c:30]3[cH:31][c:32]([C:40]([F:41])([F:42])[F:43])[cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]3)=[O:44])[c:14](-[c:16]3[c:17]([CH3:23])[cH:18][c:19]([F:22])[cH:20][cH:21]3)[cH:15]2)[CH2:8][CH2:7][CH:2]1[C:3](=[O:4])[O:5][CH3:6]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5711e7f4a32d45ec8032bf026d641aa9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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