Acetone → 3-Bromo-4-[(2,4-difluorophenyl)methoxy]-1-[(3-fluorophenyl)methyl]-2(1H)-pyridinone
Reaction equation
[Br:1][c:2]1[c:3](=[O:17])[n:4]([CH2:9][c:10]2[cH:11][c:12]([F:16])[cH:13][cH:14][cH:15]2)[cH:5][cH:6][c:7]1[OH:8].[CH3:34][C:35](=[O:36])[CH3:37].[F:24][c:25]1[c:26]([CH2:27][Br:28])[cH:29][cH:30][c:31]([F:33])[cH:32]1.[K+:18].[K+:19].[O-:20][C:21]([O-:22])=[O:23]>>[Br:1][c:2]1[c:3](=[O:17])[n:4]([CH2:9][c:10]2[cH:11][c:12]([F:16])[cH:13][cH:14][cH:15]2)[cH:5][cH:6][c:7]1[O:8][CH2:27][c:26]1[c:25]([F:24])[cH:32][c:31]([F:33])[cH:30][cH:29]1Participants
6
Sources & evidence
- ORD record
- ord-701167633d54499a85a0eeda063890a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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