Bicarbonate Ion → 5-Bromo-3-(trifluoromethyl)pyridin-2-amine
Reaction equation
[CH3:25][C:26]#[N:27].[F:1][C:2]([c:3]1[c:4]([NH2:9])[n:5][cH:6][cH:7][cH:8]1)([F:10])[F:11].[Na+:24].[O-:20][C:21]([OH:22])=[O:23].[O:12]=[C:13]1[N:14]([Br:19])[C:15](=[O:16])[CH2:17][CH2:18]1>>[F:1][C:2]([c:3]1[c:4]([NH2:9])[n:5][cH:6][c:7]([Br:19])[cH:8]1)([F:10])[F:11]Participants
6
Sources & evidence
- ORD record
- ord-4a6dc5f9a9484a5ea73cb9f4eff0bd63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…