Bicarbonate Ion → 2-Methyl-2-{[4-({[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}methyl)-1,3-thiazol-2-yl]thio}propionic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([CH3:9])[S:10][c:11]1[s:12][cH:13][c:14]([CH2:16][O:17][CH2:18][c:19]2[cH:20][cH:21][c:22]([Br:25])[cH:23][cH:24]2)[n:15]1)=[O:26].[C:48](=[O:49])([O-:50])[OH:51].[F:27][C:28]([c:29]1[cH:30][cH:31][c:32]([O:35][B:36]([OH:37])[OH:38])[cH:33][cH:34]1)([F:39])[F:40].[Na+:52].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[OH2:41].[cH:53]1[cH:54][cH:55][c:56]([P:57]([Pd:58]([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([P:78]([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[P:97]([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)([c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)[cH:128][cH:129]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([CH3:9])[S:10][c:11]1[s:12][cH:13][c:14]([CH2:16][O:17][CH2:18][c:19]2[cH:20][cH:21][c:22](-[c:32]3[cH:31][cH:30][c:29]([C:28]([F:27])([F:39])[F:40])[cH:34][cH:33]3)[cH:23][cH:24]2)[n:15]1)=[O:26]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8b0025c2e13d484b85aab2322b0d4741
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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