2-Methylpyridine-4-boronic acid → N-(6-(6-chloro-5-(3-(difluoromethoxy)phenylsulfonamido)pyridin-3-yl)-3-(2-methylpyridin-4-yl)imidazo[1,2-b]pyridazin-2-yl)acetamide
Reaction equation
[CH3:36][c:37]1[n:38][cH:39][cH:40][c:41]([B:43]([OH:44])[OH:45])[cH:42]1.[Cl:1][c:2]1[c:3]([NH:22][S:23](=[O:24])(=[O:25])[c:26]2[cH:27][c:28]([O:32][CH:33]([F:34])[F:35])[cH:29][cH:30][cH:31]2)[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]3[n:12]([n:13]2)[c:14]([I:21])[c:15]([NH:17][C:18]([CH3:19])=[O:20])[n:16]3)[cH:6][n:7]1>>[Cl:1][c:2]1[c:3]([NH:22][S:23](=[O:24])(=[O:25])[c:26]2[cH:27][c:28]([O:32][CH:33]([F:34])[F:35])[cH:29][cH:30][cH:31]2)[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]3[n:12]([n:13]2)[c:14](-[c:41]2[cH:40][cH:39][n:38][c:37]([CH3:36])[cH:42]2)[c:15]([NH:17][C:18]([CH3:19])=[O:20])[n:16]3)[cH:6][n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b4dd012638474b3a93bee58edb13ec12
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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