Acetonitrile → tert-butyl N-[1-[(7-methoxy-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)carbamoyl]pyrrolidin-3-yl]carbamate

HRID 155429Notes

Reaction equation

HRID 155429 reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27]([NH:28][CH:29]1[CH2:30][NH:31][CH2:32][CH2:33]1)=[O:34].[CH3:35][C:36]#[N:37].[c:1]1([O:2][C:8]([NH:9][c:10]2[s:11][c:12]3[n:13][cH:14][n:15][c:16]([O:19][CH3:20])[c:17]3[n:18]2)=[O:21])[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[C:8]([NH:9][c:10]1[s:11][c:12]2[n:13][cH:14][n:15][c:16]([O:19][CH3:20])[c:17]2[n:18]1)(=[O:21])[N:31]1[CH2:30][CH:29]([NH:28][C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:34])[CH2:33][CH2:32]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 2757234tert-butyl N-(pyrrolidin-3-yl)carbamateHCID 59011944(7-Methoxy-thiazolo[5,4-d]pyrimidin-2-yl)-carbamic acid phenyl ester

Product 1

HCID 72489370tert-butyl N-[1-[(7-methoxy-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)carbamoyl]pyrrolidin-3-yl]carbamate

Sources & evidence

ORD record
ord-13ee0d8877ce468eadff21103491df27
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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