5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → (RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone

HRID 1554601Notes

Reaction equation

HRID 1554601 reaction equation
[F:17][c:18]1[cH:19][cH:20][c:21](-[c:24]2[c:25]([C:30](=[O:31])[OH:32])[n:26][c:27]([CH3:29])[s:28]2)[cH:22][cH:23]1.[s:1]1[c:2]2[c:3]([cH:4][c:5]1[CH2:6][CH:7]1[NH:8][CH2:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][cH:15][cH:16]2>>[s:1]1[c:2]2[c:3]([cH:4][c:5]1[CH2:6][CH:7]1[N:8]([C:30]([c:25]3[c:24](-[c:21]4[cH:20][cH:19][c:18]([F:17])[cH:23][cH:22]4)[s:28][c:27]([CH3:29])[n:26]3)=[O:31])[CH2:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][cH:15][cH:16]2

Participants

3

Reactant 2

HCID 223241255-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 23146368HCID 23146368, compound

Product 1

HCID 23146275(RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone

Sources & evidence

ORD record
ord-6c39f1cad172497dbf4a72a002a543bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…