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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1554737Generated: October 30, 2026

1,2-Dichloroethane → 2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenylpiperidin-1-yl)carbonyl]benzoic acid

https://huagongshe.com/reaction/1554737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantPhthalic AnhydrideHCID 6811—
ReactantTriethylamineHCID 8471—
Reactant2-Methyl-1-{8-[2-(4-phenyl-4-piperidinyl)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}-1H-benzimidazoleHCID 58727827—
Product2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenylpiperidin-1-yl)carbonyl]benzoic acidHCID 54585005—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-83955b4561ba44daa964bb7ae48cc6f7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)