Sodium ion → tert-Butyl 4-(thiazol-5-ylmethyl)piperazine-1-carboxylate

HRID 1554884Notes

Reaction equation

HRID 1554884 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[C:21]([O:22][BH-:23]([O:24][C:25](=[O:26])[CH3:27])[O:28][C:29](=[O:30])[CH3:31])(=[O:32])[CH3:33].[Na+:34].[s:14]1[cH:15][n:16][cH:17][c:18]1[CH:19]=[O:20]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:19][c:18]2[s:14][cH:15][n:16][cH:17]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 143452tert-Butyl piperazine-1-carboxylateHCID 2724942TriacetoxyborohydrideHCID 27735771,3-Thiazole-5-carbaldehyde

Product 1

HCID 57897199tert-Butyl 4-(thiazol-5-ylmethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-122ac64e1ec84bc185ce86cc40d1a718
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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