Methanol → 1-{2-[4-({[5-chloro-6-(hydroxymethyl)-3-pyridinyl]methyl}amino)-1-piperidinyl]ethyl}-7-(methyloxy)-1,5-naphthyridin-2(1H)-one
Reaction equation
[C:34]([O:35][BH-:36]([O:37][C:38](=[O:39])[CH3:40])[O:41][C:42](=[O:43])[CH3:44])(=[O:45])[CH3:46].[C:48]([O:49][BH-:50]([O:51][C:52](=[O:53])[CH3:54])[O:55][C:56](=[O:57])[CH3:58])(=[O:59])[CH3:60].[CH3:64][OH:65].[Cl:23][c:24]1[cH:25][c:26]([CH:32]=[O:33])[cH:27][n:28][c:29]1[CH2:30][OH:31].[Cl:61][CH2:62][Cl:63].[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][n:10]2[c:11](=[O:22])[cH:12][cH:13][c:14]3[n:15][cH:16][c:17]([O:20][CH3:21])[cH:18][c:19]23)[CH2:6][CH2:7]1.[Na+:47]>>[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][n:10]2[c:11](=[O:22])[cH:12][cH:13][c:14]3[n:15][cH:16][c:17]([O:20][CH3:21])[cH:18][c:19]23)[CH2:6][CH2:7]1)[CH2:32][c:26]1[cH:25][c:24]([Cl:23])[c:29]([CH2:30][OH:31])[n:28][cH:27]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-80ef4ddf74e44de1888f894ceb897450
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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