Acetonitrile → 1-{2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-dibenzo[de,h]isoquinolin-11-yl}-3-[4-(trifluoromethoxy)phenyl]thiourea
Reaction equation
[CH3:40][C:41]#[N:42].[F:26][C:27]([O:28][c:29]1[cH:30][cH:31][c:32]([N:35]=[C:36]=[S:37])[cH:33][cH:34]1)([F:38])[F:39].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]3[c:9]4[c:10]([cH:23][cH:24][cH:25]3)[C:11](=[O:22])[N:12]([CH2:17][CH2:18][N:19]([CH3:20])[CH3:21])[C:13](=[O:16])[c:14]4[c:15]12>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]3[c:9]4[c:10]([cH:23][cH:24][cH:25]3)[C:11](=[O:22])[N:12]([CH2:17][CH2:18][N:19]([CH3:20])[CH3:21])[C:13](=[O:16])[c:14]4[c:15]12)[C:36]([NH:35][c:32]1[cH:31][cH:30][c:29]([O:28][C:27]([F:26])([F:38])[F:39])[cH:34][cH:33]1)=[S:37]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e6c7c1b56f9342cf9714d45927c2e891
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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