1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → 6-{4-Fluoro-2-[3-fluoro-4-(2-piperidin-1-ylethoxy)phenylamino]phenyl}naphthalen-2-ol
Reaction equation
[Br:21][c:22]1[cH:23][cH:24][c:25]([O:26][CH2:27][CH2:28][N:29]2[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]2)[c:35]([F:36])[cH:37]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:6]2[cH:7][cH:8][c:9]3[c:10]([cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16]3)[cH:17]2)[c:18]([NH2:19])[cH:20]1.[F:38][c:39]1[cH:40][cH:41][c:42](-[c:62]2[cH:63][c:64]3[cH:65][cH:66][c:67]([O:72][CH3:73])[cH:68][c:69]3[cH:70][cH:71]2)[c:43]([NH:45][c:46]2[cH:47][c:48]([F:61])[c:49]([O:52][CH2:53][CH2:54][N:55]3[CH2:56][CH2:57][CH2:58][CH2:59][CH2:60]3)[cH:50][cH:51]2)[cH:44]1>>[F:38][c:39]1[cH:40][cH:41][c:42](-[c:62]2[cH:63][c:64]3[cH:65][cH:66][c:67]([OH:72])[cH:68][c:69]3[cH:70][cH:71]2)[c:43]([NH:45][c:46]2[cH:47][c:48]([F:61])[c:49]([O:52][CH2:53][CH2:54][N:55]3[CH2:56][CH2:57][CH2:58][CH2:59][CH2:60]3)[cH:50][cH:51]2)[cH:44]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-9a38077f469d499f886eeac450663b4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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