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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1555771Generated: October 26, 2026

Tetrahydrofuran → 3-(2,4-Dichloro-pyrimidin-5-yl)-2-(2,5-dimethoxy-phenyl)-propionic acid ethyl ester

https://huagongshe.com/reaction/1555771

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantCyclohexylisopropylamineHCID 62386—
ReactantEthyl 2,5-dimethoxyphenylacetateHCID 5055243—
Reactant2,4-Dichloro-5-(iodomethyl)pyrimidineHCID 21939352—
ReactantButyllithiumHCID 178418339—
Product3-(2,4-Dichloro-pyrimidin-5-yl)-2-(2,5-dimethoxy-phenyl)-propionic acid ethyl esterHCID 21044301—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-ca9674035be049bb9ae838c070bb4e58
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)