Pyridine → 7-Chloro-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-thione

HRID 155589Notes

Reaction equation

HRID 155589 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:16]1)[NH:7][C:8](=[O:15])[c:9]1[c:10]([cH:12][s:13][cH:14]1)[NH:11]2.[P:17]12(=[S:18])[S:19][P:20]3(=[S:30])[S:21][P:22](=[S:28])([S:23][P:24](=[S:27])([S:25]3)[S:26]1)[S:29]2.[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:16]1)[NH:7][C:8](=[S:18])[c:9]1[c:10]([cH:12][s:13][cH:14]1)[NH:11]2

Participants

4

Reactant 3

HCID 1049PyridineHCID 14817Phosphorus sulfide (P2S5)HCID 6195267-Chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one

Product 1

HCID 125216547-Chloro-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-thione

Sources & evidence

ORD record
ord-3589a1919cb3470b8f38c5cf41ba4f6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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