Potassium Cation → 4-(4-Fluorophenyl)-7-{[{5-[1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl}(methyl)amino]methyl}-2H-chromen-2-one

HRID 1555913Notes

Reaction equation

HRID 1555913 reaction equation
[CH3:34][I:35].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10](=[O:33])[o:11][c:12]3[cH:13][c:14]([CH2:18][NH:19][c:20]4[o:21][c:22]([C:25]([CH2:26][CH3:27])([C:28]([F:29])([F:30])[F:31])[OH:32])[n:23][n:24]4)[cH:15][cH:16][c:17]23)[cH:6][cH:7]1.[K+:36].[K+:37].[O-:38][C:39]([O-:40])=[O:41]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10](=[O:33])[o:11][c:12]3[cH:13][c:14]([CH2:18][N:19]([c:20]4[o:21][c:22]([C:25]([CH2:26][CH3:27])([C:28]([F:29])([F:30])[F:31])[OH:32])[n:23][n:24]4)[CH3:39])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 6328Methyl iodideHCID 19660Carbonate IonHCID 118561694-(4-fluorophenyl)-7-[({5-[1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl}amino)methyl]-2H-chromen-2-one

Product 1

HCID 118556254-(4-Fluorophenyl)-7-{[{5-[1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl}(methyl)amino]methyl}-2H-chromen-2-one

Sources & evidence

ORD record
ord-4aa24bb51c8449e98e7c72679ed98baf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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