5-bromo-N-(2-(dimethylamino)ethyl)thiophene-2-sulfonamide → 5-[7-Difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (2-dimethylamino-ethyl)-amide
Reaction equation
[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:15]1[cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][cH:19][cH:20]1)[cH:10][c:11]2[CH:12]([F:13])[F:14].[CH3:25][N:26]([CH2:27][CH2:28][NH:29][S:30](=[O:31])(=[O:32])[c:33]1[s:34][c:35]([Br:38])[cH:36][cH:37]1)[CH3:39]>>[C:1](#[C:2][c:35]1[s:34][c:33]([S:30]([NH:29][CH2:28][CH2:27][N:26]([CH3:25])[CH3:39])(=[O:31])=[O:32])[cH:37][cH:36]1)[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:15]1[cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][cH:19][cH:20]1)[cH:10][c:11]2[CH:12]([F:13])[F:14]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-032ab8758e0c4766a2928a6876f9c2ef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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