Dimethyl Sulfoxide → 6-cyclopentyl-6-[2-(3,5-diethyl-4-hydroxyphenyl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one

HRID 1556242Notes

Reaction equation

HRID 1556242 reaction equation
[CH3:1][c:2]1[n:3][c:4]2[n:5]([c:6]([CH3:8])[cH:7]1)[n:9][c:10]([CH:12]=[O:13])[n:11]2.[CH3:40][S:41]([CH3:42])=[O:43].[CH:14]1([C:19]2([CH2:27][CH2:28][c:29]3[cH:30][c:31]([CH2:38][CH3:39])[c:32]([OH:37])[c:33]([CH2:35][CH3:36])[cH:34]3)[CH2:20][C:21](=[O:26])[CH2:22][C:23](=[O:25])[O:24]2)[CH2:15][CH2:16][CH2:17][CH2:18]1>>[CH3:1][c:2]1[n:3][c:4]2[n:5]([c:6]([CH3:8])[cH:7]1)[n:9][c:10]([CH2:12][C:22]1=[C:21]([OH:26])[CH2:20][C:19]([CH:14]3[CH2:15][CH2:16][CH2:17][CH2:18]3)([CH2:27][CH2:28][c:29]3[cH:30][c:31]([CH2:38][CH3:39])[c:32]([OH:37])[c:33]([CH2:35][CH3:36])[cH:34]3)[O:24][C:23]1=[O:25])[n:11]2

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 236352265,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbaldehydeHCID 587625206-cyclopentyl-6-[2-(3,5-diethyl-4-hydroxyphenyl)ethyl]dihydro-2H-pyran-2,4(3H)-dione

Product 1

HCID 587625006-cyclopentyl-6-[2-(3,5-diethyl-4-hydroxyphenyl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one

Sources & evidence

ORD record
ord-a8b70c2089434f1da93aefd9b469e52c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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