Dichloromethane → N-(4-{[(5-chloro-3-methyl-pyridin-2-ylmethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amino]-methyl}-3-hydroxymethyl-benzyl)-acetamide

HRID 1556349Notes

Reaction equation

HRID 1556349 reaction equation
[Cl:26][c:27]1[cH:28][c:29]([CH3:35])[c:30]([CH:33]=[O:34])[n:31][cH:32]1.[Cl:36][CH2:37][Cl:38].[OH:1][CH2:2][c:3]1[cH:4][c:5]([CH2:6][NH:7][C:8]([CH3:9])=[O:10])[cH:11][cH:12][c:13]1[CH2:14][NH:15][CH:16]1[CH2:17][CH2:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][n:24][c:25]21>>[OH:1][CH2:2][c:3]1[cH:4][c:5]([CH2:6][NH:7][C:8]([CH3:9])=[O:10])[cH:11][cH:12][c:13]1[CH2:14][N:15]([CH:16]1[CH2:17][CH2:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][n:24][c:25]21)[CH2:33][c:30]1[c:29]([CH3:35])[cH:28][c:27]([Cl:26])[cH:32][n:31]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 67272098N-{3-hydroxymethyl-4-[(5,6,7,8-tetrahydro-quinolin-8-ylamino)-methyl]-benzyl}-acetamideHCID 722140555-Chloro-3-methylpicolinaldehyde

Product 1

HCID 67272829N-(4-{[(5-chloro-3-methyl-pyridin-2-ylmethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amino]-methyl}-3-hydroxymethyl-benzyl)-acetamide

Sources & evidence

ORD record
ord-13bd2a4b4471409099ec14fff473f9b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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