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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 155684Generated: October 29, 2026

Potassium Cation → 1-(2,4-Difluoro-benzyl)-6-[5-(6-methylsulfanyl-pyridin-3-yl)-thiophen-2-yl]-2-oxo-4-trifluoromethyl-1,2-dihydro-pyridine-3-carbonitrile

https://huagongshe.com/reaction/155684

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantCarbonate IonHCID 19660—
Reactant6-(5-Bromo-thiophen-2-yl)-1-(2,4-difluoro-benzyl)-2-oxo-4-trifluoromethyl-1,2-dihydro-pyridine-3-carbonitrileHCID 11605314—
Reactant2-(Methylsulfanyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineHCID 44755191—
ReactantHCID 178420554HCID 178420554—
Product1-(2,4-Difluoro-benzyl)-6-[5-(6-methylsulfanyl-pyridin-3-yl)-thiophen-2-yl]-2-oxo-4-trifluoromethyl-1,2-dihydro-pyridine-3-carbonitrileHCID 59726624—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-93aefcd69e1143d09555a767385252a5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)